Fat Loss Biology

Leptin is the Master Fat Hormone, and it works by signaling the hypothalamus of the brain. The questions for fat loss now under study are starting to look at how leptin and HCG interact. The idea is that they may be using the same or similar brain receptors. It is a great topic for understanding more about how HCG works.

Image via Wikipedia

Here is a great article that goes down the road of explaining leptin metabolism. Let me know if you have any questions, class!

Dr Mel Siff Discusses Leptin and Fat Loss

Here are some extracts from a highly informative article on leptin, a hormone secreted by fat cells that influences energy expenditure and food intake.

All the best in fat loss,
Dr. D

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5 Comments so far »

  1. by Fat Loss Hormone Balance |


    […] Here is my link: Leptin and Fat Loss During the HCG Diet […]

  2. by Robin Woodall


    I’ve written a modern hypothesis for why hCG prevents starvation in my new book, Weight-Loss Apocalypse. Leptin is the link between hCG and energy homeostasis during the hCG protocol. NO DOUBT ABOUT IT.

  3. by Dr. Dennis Clark


    Hi, Robin:

    It is nice to meet a like-minded thinker. Your link did not take me to anyplace on your site where I could see what you have to say about your hypothesis, nor could I find any mention of it by searching several pages there. Researchers have been looking into the link between leptin and hCG for some time now. Indeed, just moments ago I did a search on Pubmed, for the terms ‘leptin AND hCG’ together, and came up with 69 published articles on the subject since 1997.

    All the best,

  4. by Mike


    Dr. Clark,

    Your bio says you have a PhD in botany. You are not a medical doctor are you? You sell your hCG diet protocol for nearly $645 for a 43 day plan, so it is clear that you have lots to gain by marketing your hCG plan.

    For those of us who don’t want to dive into the next very expensive diet fad without due dilligence as to the short and long term effects of this hormone therapy, please explain more on the connection between Leptin and hCG. Bottom line is: for the $645 you demand, do you guarantee that there are no ill-effects to the consumer? Do you have a medical partner in your business, that assures us lay-persons this product is 100% safe?


    Mike M.
    Beaverton, OR

  5. by Dr. Dennis Clark


    Hi, Mike:

    You have great questions. I have gone to great lengths to explain all that I know and do. You can find all the answers you seek by doing good research, starting on this blog. Thanks for your interest. I am not sure that you are expressing distrust, although that is normal and even advisable when doing business with unknown persons on the internet. My best advice to you is to seek out a local clinic in your area so you can work with people on a face to face basis.

    All the best,

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